The Least Pygmy-owl (Glaucidium minutissimum), also known as Sick's Pygmy-owl, is a small owl in the typical owl family. It has been argued that the here used scientific name actually belongs to the Pernambuco Pygmy-owl, in which case the Least Pygmy-owl should be referred to G. sicki (König & Weick, 2005). This has not gained widespread recognition.

It is found in eastern Brazil and far eastern Paraguay. It inhabits tropical moist evergreen forests and edges as well as open bush canopy. It is one of the smallest South American owls, averaging at 45 grams (1.6 oz) and 15 cm (6 in).

Formerly, this species included the Colima, Tamaulipas, Central American, Subtropical, and Baja Pygmy-owl as subspecies.